neuroinflammation

Inflammation, the Immune System, and the Brain – New Models of Disease

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In recent years, science is finally beginning to grasp the obvious fact that the human body is a system, so that when something goes wrong in one part of the organism, it has effects in other parts of the organism as well. The most obvious example of this is the new focus on the microbiome … Read more

Inflammasomes in Neuroinflammation and Changes in Brain Function: A Focused Review

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This post serves as a follow-up to yesterday’s post on the relationship between trauma exposure and neuroinflammation. This review article comes from Frontiers in Neuroendocrine Science. This is from the abstract: Inflammasomes activate pro-inflammatory caspases 1 and 5, which then cleave the precursor forms of pro-inflammatory cytokines IL-1β, IL-18, and IL-33 into their active forms. … Read more